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Reverse engineering gene networks
Colloquium| Speaker: | M.K. Stephen Yeung, Boston University |
| Location: | 693 Kerr |
| Start time: | Fri, Jan 17 2003, 4:10PM |
Description
We present a scheme to reverse-engineer gene networks on a
genome-wide scale using a relatively small amount of gene
expression data from microarray experiments. It uses singular
value decomposition to construct a family of solutions and then
identify the unique solution by robust regression. Our
algorithm has $O(\log N)$ sampling complexity and $O(N^4)$
computational complexity. We test and validate our approach in
a series of numerical experiments on model gene networks.
(3:45 Refreshments will be served before the talk in 551 Kerr Hall)