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Using knot theory to understand DNA structure and function.

Colloquium

Speaker: David Letscher, UCSD
Location: 693 Kerr
Start time: Mon, May 10 1999, 4:10PM

Description

During the life span of bacterial its DNA can form knots and links. In particular, during replication the duplicate copy of the DNA strand links itself to the original. A model will be given for how topoisomerases can recognize knotting or linking from purely local information and through a series of crossing changes produce the unknot or unlink. Studying these biological processes has also led to some conjectures in knot theory that will be discussed.